One in five ischemic stroke survivors will have another stroke within 5 years

Did you know that despite guideline-recommend antiplatelet therapy, the 1-year recurrence rate after an ischemic stroke ranges from 5.7% to 17.7%, and, at 5 years, increases to 14–26%? 

 

Recurrence of ischemic stroke significally increases the risk of death

While secondary prevention strategies have improved recurrence rates, too many of your patients are vulnerable, and death from recurrent stroke remains high.

Bar graph
“A stroke is like a tsunami. I cannot let another one take me under again.”
risk of dementia

Recurrent and more severe ischemic strokes tend to be more disabling and increase the risk of dementia

Survivors with higher disability scores after an ischemic stroke are also more likely to suffer subsequent strokes and major cardiovascular events.

Age

Age, race, and socioeconomic factors affect the rates of stroke recurrence

Do you know that the risk of secondary stroke increases in marginalized groups, who may suffer disproportionately from healthcare inequity? Older people, Black adults, and those of low socioeconomic status all have an increased risk of suffering a second stroke.

According to an observational study (N=3816) in Cincinnati, for example, socioeconomic and health inequities likely contributed to higher risk of recurrent stroke in Black adults.

“The thought of having 
another stroke? Scary.”

Regional incidence of ischemic stroke and stroke recurrence

While stroke and stroke recurrence remain a global issue, studies investigating the incidence and effects of stroke show striking country variations.


For example, did you know that in Finland, recurrent ischemic stroke increases the risk of death by as much as 16.7-fold (N=970, p=0.005)? Or that in the USA, the incidence of ischemic stroke is as high as 87%, and is associated with a steep increase in disability after the stroke?

Recurrent stroke
Image created from Feigin, et al. 2024 and Feigin, et al. 2023.

Unmet needs, unseen risks

Stroke is the second leading cause of death globally. For survivors, the impact on every day life can be severe. Despite adherence to guideline recommendations for stroke prevention, a significant proportion of survivors experience another stroke.

Secondary stroke
deserves another look #NoToTwo

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